The ZRT Laboratory Blog

The ZRT Blog is an extensive resource for patients and health care providers searching for health and hormone testing information. Here, you can read about ZRT’s cutting edge research, advances in testing, wellness advice, and health industry highlights.



Jim Paoletti

Jim Paoletti, FAARFM, FIACP, is Director of Education for Power2Practice and author of A Practitioner's Guide to Physiologic Bioidentical Hormone Balance.
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Recent Posts

How to Convert Patients to BHRT from Conventional Therapies

Posted by Jim Paoletti on Thursday, 23 March

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Practice Takeaway: 

I always try to taper the estrogen dose down over a period of 2-6 months depending on the individual’s difficulty with withdrawal symptoms. Once I have the patient on a lower dose (Premarin 0.3 mg or Estrace 0.25 mg every other day at the most), I will switch over to a bi-est consisting of 50% estradiol and 50% estriol.

The reason for this is, if you stop the estrogen abruptly or decrease the dose too quickly, the patient can experience severe withdrawal symptoms of estrogen deficiency. 

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Testosterone Replacement Therapy: Ensuring an Accurate Dose!

Posted by Jim Paoletti on Thursday, 07 July

scientists_deciding.jpgTestosterone replacement therapy has the potential to drastically improve quality of life of those who need it. However, many men who begin topical testosterone are given too much of the hormone.

Explanations for this erroneous tendency are rooted in incorrect dosing principles that have been established on false assumptions, misconceptions, invalid conclusions and aggressive marketing instead of physiology and science.

Why are testosterone replacement standards and prescribing processes so frequently misguided? 

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Determining the Functional Causes of Hypothyroid Symptoms

Posted by Jim Paoletti on Tuesday, 08 December

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Hypothyroidism is defined as “lack of thyroid hormone production from the thyroid gland.” 

However, many patients who produce sufficient hormone from the gland still suffer from low thyroid symptoms. 

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Confused About Hormone Therapy Terminology?

Posted by Jim Paoletti on Friday, 16 October

patients ask about bioidential hormone therapy

When a patient says that she wants “natural” hormone therapy, does the term mean the same thing to you as it does to her?

Let’s explore that question further by dissecting the terminology most commonly used by patients (and even some experts) when discussing hormone restoration therapy: “natural,” “synthetic” and “bio-identical.”

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