The ZRT Laboratory Blog

The ZRT Blog is an extensive resource for patients and health care providers searching for health and hormone testing information. Here, you can read about ZRT’s cutting edge research, advances in testing, wellness advice, and health industry highlights.

Testosterone Replacement Therapy: Ensuring an Accurate Dose!

Posted by Jim Paoletti on Thursday, 07 July

scientists_deciding.jpgTestosterone replacement therapy has the potential to drastically improve quality of life of those who need it. However, many men who begin topical testosterone are given too much of the hormone.

Explanations for this erroneous tendency are rooted in incorrect dosing principles that have been established on false assumptions, misconceptions, invalid conclusions and aggressive marketing instead of physiology and science.

Why are testosterone replacement standards and prescribing processes so frequently misguided? 

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3 Keys to Preventing Prostate Cancer

Posted by Dr. Allison Smith on Friday, 24 June

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Getting an early jump on a disease process like cancer makes treatment exponentially easier and outcomes generally better.

Under the current guidelines, that early jump on prostate cancer starts at age 55 for men at low to moderate risk and 40-45 for men at high risk. It takes years for cancer to grow to a detectable point after the tumor's initial induction from a normal cell to a cancerous one.

There's been a lot of research done to determine what those inducers are and how they work. Three of these inducers are simple to test for and completely modifiable with treatment and/or avoidance:

  • Bisphenol A
  • Arsenic
  • Catechol estrogens

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Andropause: Real Men Go For Balance

Posted by Candace Burch on Friday, 17 June

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The first thing a man entering andropause generally notices is a subtle downward shift in strength and energy as hormone levels taper off. Muscle tone and stamina are the first to go and he starts to gain weight and that "spare tire." He may also develop a voracious appetite and food cravings he never had before. As symptoms kick in at mid-life, hormone testing can identify hidden imbalances that complicate symptoms of andropause and contribute to rapid aging. 

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SHBG – A Modulator to be Modulated

Posted by Dr. Allison Smith on Tuesday, 21 July

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SHBG, or Sex Hormone Binding Globulin, controls testosterone effect in both men and women by modulating changes in sex steroid levels. When SHBG goes up, free testosterone goes down.

I like to think of SHBG as a sponge that soaks up androgens and to some degree estrogens as well.

Since it binds so specifically and tightly to testosterone, it makes up part of the equation that equals androgen excess or androgen deficiency. Knowing how to manipulate SHBG can be a useful tool in a number of scenarios.

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