The ZRT Laboratory Blog

The ZRT Blog is an extensive resource for patients and health care providers searching for health and hormone testing information. Here, you can read about ZRT’s cutting edge research, advances in testing, wellness advice, and health industry highlights.

Mood and Menopause – Going Through "The Change"

Posted by Dr. Kate Placzek on Friday, 01 December

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Not quite menopause. Throwing blankets off at night, keeping awake. Fatigue and irritation punctuated throughout the day by heat dissipating from every pore, clouding thoughts, reinforcing forgetfulness. Hair falling out so stubbornly fast. Clothes choosing when to fit. Flooding periods coming sporadically, unexpectedly. They call it “the change of life” – but I feel like a different person altogether. What is happening?         

In perimenopause, the physiological landscape is subject to tremendous change with estradiol and progesterone at the heart of the transition. Progesterone levels fall quickly – no ovulation – no corpus luteum – no progesterone. Estradiol, on the other hand, does not give up so easily. Estradiol levels continue to rise and fall – reliable, steady, wave-like – a biological rollercoaster – approaching the halting rhythms of reproductive senescence. In the context of very low progesterone, these dramatic peaks and troughs in estradiol levels, give rise to systemic consequences and unrelenting symptoms of the menopausal transition. 

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Brussels Sprouts & Healthy Estrogen Metabolism

Posted by ZRT Laboratory on Friday, 21 July

Brussel Sprouts and Good EstrogenYou might ask what Brussels sprouts and estrogens are doing in the same sentence, but I am here to tell you that there is a connection.

Brussels sprouts are the cruciferous connection to healthy hormone metabolism. These age-old options –including cabbage, broccoli, bok choy and cauliflower – have gained new acclaim today as dietary super foods. These plants, cultivated for centuries and originally used as medicines, can nourish us towards superior health and hormone balance.

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A Year of Saliva Testing in Research

Posted by Dr. Alison McAllister on Friday, 23 December

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I wanted to share a few of the studies using saliva testing that were published in the literature in 2016.

Just a hint, if you want to search for articles on saliva testing, use pubmed.gov and search saliva estradiol (or progesterone, testosterone etc.).

Be aware that saliva hormone testing is so standard in the research world that rarely is it mentioned in the titles of the papers. Over 310 studies were published in 2016 using saliva testing – 61 studies for testosterone and 189 studies on cortisol, while poor progesterone was neglected with only 14 studies this last year.

It’s always good to know that the work that ZRT has been doing for almost 20 years in the field of saliva testing is still cutting edge and useful. 

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Menopause – Is It All In Your Head?

Posted by Dr. Kate Placzek on Friday, 03 June

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Estrogen. 

We've heard Dr. Zava call it the "angel of life, and the angel of death." Too much can be hazardous. Too little can be problematic also. 

Not many people realize this, but estrogen plays a role in more bodily functions than just reproduction. In fact, estrogen has many important functions in the brain. 

Studies show that decreasing levels of estrogen can cause two of the most common perimenopause symptoms hot flashes and mood fluctuations. Curious how this happens? Read on to learn the details of this biochemistry. 

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