The ZRT Laboratory Blog

The ZRT Blog is an extensive resource for patients and health care providers searching for health and hormone testing information. Here, you can read about ZRT’s cutting edge research, advances in testing, wellness advice, and health industry highlights.

The Impact of Hormones on Serotonin in Depression

Posted by Dr. Kate Placzek on Friday, 09 February

Serotonin Blog Images-609310-edited.jpgSerotonin, or rather its deficiency, frequently steals the spotlight in conversations regarding depression.  Initially discovered as a component of serum in 1948 to regulate vasoconstriction (serotonin = serum + tone), the role of serotonin in depressive disorders wasn't implied until a few years later. Since then, much effort has been dedicated by scientists and clinicians alike to understand the wondrous complexity of the seemingly inscrutable code that is serotonin neurotransmission. In fact, some of the major breakthroughs in psychopharmacology happened with serotonin in mind – the discovery of selective serotonin reuptake inhibitors (SSRIs) prominently expanded the therapeutic toolbox for mental health practitioners.      

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