The ZRT Laboratory Blog

The ZRT Blog is an extensive resource for patients and health care providers searching for health and hormone testing information. Here, you can read about ZRT’s cutting edge research, advances in testing, wellness advice, and health industry highlights.

Re-assessing the Notion of "Pregnenolone Steal"

Posted by Dr. Thomas Guilliams on Wednesday, 21 June

ThinkstockPhotos-687447022-pregnenolone-.jpgWhen clinicians measure salivary cortisol and DHEA (DHEA-S) to assess stress and HPA axis function, it is common to find DHEA levels below the reference range in a number of individuals. A common explanation for the depletion of DHEA and other hormones (e.g., progesterone, testosterone) due to chronic stress is the phenomenon known as "pregnenolone steal."

The pregnenolone steal notion basically states that since all steroid hormones use pregnenolone (derived from cholesterol) as a precursor, the elevated secretion of cortisol caused by acute or chronic stress will inevitably result in less available pregnenolone to serve as a precursor for the production of DHEA and other down-stream hormones.

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Examining the "Warrior Gene" - MAOA & Aggression

Posted by Dr. Kate Placzek on Friday, 02 June

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Aggression is deeply rooted in our genetic foundation. Yet it is a double-edged sword: on one side, aggression communicates dominance, an exaggerated hostile manifestation and a willful attempt to harm. On the other, aggression is innate and essential to the human condition, even instrumental to our survival as a species for attainment of resources, determent of competitors, and organization of social hierarchies. 

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Finally Focused: Mineral Imbalances & ADHD (Part 2: Magnesium Deficiency)

Posted by Dr. James Greenblatt on Thursday, 25 May

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In part 1 of this series, we discussed the importance of correcting trace mineral imbalances of copper and zinc to reduce behavioral symptoms and improve medication efficiency in children with ADHD. There is another nutrient that should be considered by all healthcare professionals, parents, and those struggling with ADHD: magnesium. Magnesium is a macromineral required for hundreds of the body's biochemical reactions including protein synthesis, muscle and nerve function, blood glucose control, bone development, DNA synthesis, and glutathione synthesis.

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L-Theanine in Green Tea Stimulates Neurotransmitter Production & Reduces Anxiety

Posted by Dr. Kate Placzek on Friday, 19 May

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Capable of generating higher consciousness, the human brain is truly impressive in its complexity. The brain not only controls how we feel and what we think, but also manages all aspects of our health. To understand the fundamentals of a healthy brain, we ought to first take the time to understand how it works.  In so many ways, our understanding of brain function evolved from studies on electricity.  

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